Journals of Gerontology Series A: Biological Sciences and Medical Sciences Large Type Edition
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Correction for Russanova et al., J Gerontol A Biol Sci Med Sci 59 (12) 1234-1243.
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The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 60:411-412 (2005)
© 2005 The Gerontological Society of America


FIGURE CORRECTIONS

Mapping Development-Related and Age-Related Chromatin Remodeling by a High Throughput ChIP-HPLC Approach

Valya R. Russanova, Tazuko H. Hirai, Andrei V. Tchernov and Bruce H. Howard

National Institute for Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

Figures 2Go and 4 from this article, which originally appeared in the December 2004 issue, pages 1234–1243, were inadvertently printed in black and white, on pages 1238, 1239, and 1241, instead of color. The corrected COLOR figures appear below and on the following page.



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Figure 2. Summary of chromatin mapping results. A: Continuous 2.15 Mb sequence depicted on three consecutive lines: (a), 1 Mb telomere-proximal region; (b), 150 Kb central region mapped in greater detail; (c), 1 Mb centromere-proximal region. See schematic diagram at upper right. Black vertical lines above central mapped region depict positions of primer pairs used. Vertical bars in sampled regions are not to scale. Color keys are shown at center right. For each region, red-gray-blue upper bar denotes relative histone acetylation levels, while lower red-yellow-green bar indicates change from fetal to adult pattern. Black triangle designates the position of the original h9 locus. Two gray triangles and asterisk show positions examined at multiple ages (see
Figure 3 and text). In control experiments, the mean of ratio values, represented by a set of five randomly selected chromosome positions, was 1.1 ± 0.2 (not shown). B: Summary of mapping results for subregion overlapping the MIST (mast cell immunoreceptor signal transducer) gene (see gray bar above telomere-proximal sampled sequence in (A), as well as red segment in schematic diagram at upper right). Note that the lower color key scale is adjusted to reflect greater changes in acetylation levels

 


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Figure 2. (Continued)

 


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Figure 4. Chromatin mapping: comparisons of epigenome patterns in young versus old adults. Continuous 1.06 Mb region depicted on two consecutive lines. Notations are as in
Figure 2

 

Received August 3, 2004

Accepted October 1, 2004





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