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Figure 2. Summary of chromatin mapping results. A: Continuous 2.15 Mb sequence depicted on three consecutive lines: (a), 1 Mb telomere-proximal region; (b), 150 Kb central region mapped in greater detail; (c), 1 Mb centromere-proximal region. See schematic diagram at upper right. Black vertical lines above central mapped region depict positions of primer pairs used. Vertical bars in sampled regions are not to scale. Color keys are shown at center right. For each region, red-gray-blue upper bar denotes relative histone acetylation levels, while lower red-yellow-green bar indicates change from fetal to adult pattern. Black triangle designates the position of the original h9 locus. Two gray triangles and asterisk show positions examined at multiple ages (see Figure 3 and text). In control experiments, the mean of ratio values, represented by a set of five randomly selected chromosome positions, was 1.1 ± 0.2 (not shown). B: Summary of mapping results for subregion overlapping the MIST (mast cell immunoreceptor signal transducer) gene (see gray bar above telomere-proximal sampled sequence in (A), as well as red segment in schematic diagram at upper right). Note that the lower color key scale is adjusted to reflect greater changes in acetylation levels
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